Resumen de Self-assembled monolayers for biological applications: design, processing, characterization and biological studies
Self-assembled monolayers (SAMs) is a versatile strategy for surface functionalization to achieve functional and smart materials.
In this research, SAMs on gold surfaces have been designed, processed, characterized and used as a surface biofunctionalization strategy for specific biological applications. The studies performed include the control of lipid bilayer diffusion, cell adhesion and tubulogenesis studies, and also the creation of antimicrobial surfaces.
More specifically, dynamic SAMs on surfaces whose properties can be modified with an electrochemical external stimulus have been developed and used to interrogate biological systems. The same platform has been applied to two different applications in order to overcome present challenges when performing biological studies.
The strategies used open up for new possibilities for controlled biomolecule immobilization for fundamental biological studies and biotechnology applications, at the interface of materials science and biology.
