Unraveling the roles of the arabidopsis ttl gene family in abiotic stress tolerance and hormonal responses
- Autores: Naoufal Lakhssassi
- Directores de la Tesis: Miguel A. Botella (dir. tes.), Omar Borsani Cambón (codir. tes.)
- Lectura: En la Universidad de Málaga ( España ) en 2011
- Idioma: español
- Tribunal Calificador de la Tesis: Victoriano Valpuesta (presid.), Abel Rosado Rey (secret.), Julio Salinas Muñoz (voc.), Salomé Prat (voc.), Francisco Javier Quintero Toscano (voc.)
- Materias:
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- Resumen
Tetratrico peptide thioredoxin-Like (TTL) proteins are characterized by the presence of 6 tetratrico peptide repeats (TPR) in conserved positions and a C-terminus región known as thioredoxin-like (TRXL) domain with homology to thioredoxins. In Arabidopsis thaliana, the TTLs family is composed by four members, and the analysis of double and triple mutants indicates that that TTL1, TTL3 and TTL4 have partially overlapping yet specific functions in abiotic stress tolerance while TTL2 functions in male gametophytic transmission.
Mutations on the different TTL also showed defects in vasculature development in the inflorescence stem as well as in cotyledons vein patterning, which was enhanced by increasing the number of TTL genes mutated. Since ffls mutants showed hyposensitivity to BRs but not to other hormones, indicating the TTL are specifically involved in BR responses.
Thus, this thesis assign novel functions to this essential and poorly characterized family of plant proteins and propose that TTL proteins can work as adaptors facilitating the diversification and amplification of Brassinosteroids signáis in múltiple downstream pathways affecting vein formation, vascular bundle development and abiotic stress responses.
