From pixels to particles: multi-physics meshless model of the heart

• Autores: Eric Lluch Alvarez
• Directores de la Tesis: Oscar Camara Rey (dir. tes.), Fernando García Morales (codir. tes.)
• Lectura: En la Universitat Pompeu Fabra ( España ) en 2019
• Idioma: español
• Tribunal Calificador de la Tesis: Mariano Vázquez (presid.), José Félix Rodríguez Matas (secret.), Odile Bonnefous (voc.)
• Programa de doctorado: Programa de Doctorado en Tecnologías de la Información y las Comunicaciones por la Universidad Pompeu Fabra
• Materias:
  • Matemáticas
    • Análisis y análisis funcional
      • Ecuaciones diferenciales en derivadas parciales
• Enlaces
  • Tesis en acceso abierto en: TDX
• Resumen

  • The functioning of the heart, which main role is pumping blood to the rest of the body, is the result of a complex combination of multi-scale physical processes from the molecular to the tissue level.

    The predominance of animal experiments to understand the cardiac function has a high cost and associated ethical burden. There is a growing interest for non-invasive ways of extracting measurements. Owing to improvements of numerical methods and computational infrastructure, cardiac models might provide complementary clinically-relevant information in a non-invasive way.

    The majority of cardiac models use mesh-based numerical techniques, whose performance depends on the construction of a well-defined mesh that represents the high complexity of anatomical structures such as the heart.

    This thesis presents a derivation of a fully coupled multi-physics meshless model of the heart as an alternative and provides robust evidence of its ability to simulate the heart's behavior as observed in experimental measurements.