Reactivity and impact of inorganic nanoparticles in biological environments: building up nanosafety
- Autores: Eudald Casals
- Directores de la Tesis: Victor Franco Puntes (dir. tes.), Ester Boix i Borràs (tut. tes.)
- Lectura: En la Universitat Autònoma de Barcelona ( España ) en 2012
- Idioma: inglés
- Tribunal Calificador de la Tesis: Manuel Sabés Xamaní (presid.), Jesús Martínez de la Fuente (secret.), Gertie Janneke Oostingh (voc.)
- Materias:
- Enlaces
- Tesis en acceso abierto en: TESEO
- Resumen
The aim of this work is to provide a contribution to the current knowledge of the inorganic nanoparticles full life cycle, i.e., how nanoparticles behave once are naturally or intendedly produced and are exposed to humans and the environment. The response of nanoparticles inside organisms or released to the environment is complex and diverse, and a variety of parameters are involved: nanoparticles may be aggregated into microscopic particles or embedded in exposed materials; their surfaces, which determine their bioactivity, experience constant modifications; nanoparticles may corrode and dissolve; or they can suffer morphological modifications. Thus, in biological environments, effects of nanoparticles will depend not only on their composition and initial morphological (size and shape) properties, but also on many other parameters including additives and synthesis method used and, last but not least, on their physico-chemical evolution in the exposure medium. All this has been investigated and the results are presented and discussed in this thesis.
