Información General

• Autores: Roger T. Lyland (ed. lit.), Irving B. Browning (ed. lit.)
• Editores: Nova Science Publishers
• Año de publicación: 2008
• País: España
• Idioma: español
• ISBN: 978-1604564464
• Texto completo no disponible (Saber más ...)

Resumen

• RNA interference (RNAi) is a mechanism that inhibits gene expression by causing the degradation of specific RNA molecules or hindering the transcription of specific genes. RNAi targets include RNA from viruses and transposons (probably as a form of innate immune response), and also plays a role in regulating development and genome maintenance. Small interfering RNA strands (siRNA) are key to the RNAi process, and have complementary nucleotide sequences to the targeted RNA strand. Specific RNAi pathway proteins are guided by the siRNA to the targeted messenger RNA (mRNA), where they "cleave" the target, breaking it down into smaller portions that can no longer be translated into protein. A type of RNA transcribed from the genome itself, microRNA (miRNA), works in the same way. This new book presents the latest research in the field from around the globe.

Otros catálogos

• Red de Bibliotecas Universitarias (REBIUN)

Listado de artículos

• • Applications of RNAi in C. Elegans Research

    Julian Ceron Madrigal, Juan Cabello Pardos, José Manuel Monje

    págs. 19-50

    

  • Vector-based RNAi in Chicken Embryos in vivo

    págs. 51-73

    

  • Optimal siRNA Sequence Design for RNA Interference

    págs. 75-102

    

  • SiRNA Silencing Efficacy Prediction

    págs. 103-134

    

  • RNA Interference: From Functional Genomics to Validation of Drug Targets in Helminths

    págs. 135-162

    

  • Regulation of Metabolism, Aging and Lifespan by MicroRNAs

    págs. 163-187

    

  • Gene Silencing by Double-Stranded RNA in Apis Mellifera: A Useful Reverse Genetics Approach for Studying Complex Biological Phenomena

    págs. 189-210

    

  • Induction of RNA Interference by Episomal Transcriptionally Silent Homologous DNA

    págs. 211-229

    

  • RNA Silencing and DNA Methylation in Plants

    págs. 231-257

    

  • RNA Silencing and Plant Defence Against Viral and Non-Viral Pathogens

    págs. 259-279

    

  • Polymers for siRNA Delivery in Vivo

    págs. 281-299