In vitro evaluation of antibacterial and antioxidant activity of malva sylvestris and malva pseudolavatera extracts

• Autores: Yamilet Irene Gutiérrez Gaitén, Glenda Marcela Sarmiento Tomalá, Alondra Idrovo Encalada, Zoraida del Carmen Burbano Gómez, Pilar Soledispa Cañarte, Alexandra Jenny López Barrera, Carlos Jefferson Valdiviezo, Francisca Patricia Jiménez Granizo
• Localización: Health Leadership and Quality of Life, ISSN-e 3008-8488, Vol. 3, Nº. 0, 2024 (Ejemplar dedicado a: Health Leadership and Quality of Life)
• Idioma: inglés
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• Resumen

  • In the present research work has done the evaluation of the antibacterial activity of aqueous and hydroalcoholic extracts of the leaves of Malva sylvestris and Malva pseudolavatera, against three microorganisms (Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae) and antioxidant evaluation of hydroalcoholic extracts, with the goal to provide an alternative in the treatment of infectious and chronic degenerative diseases. The antibacterial activity was performed by disk diffusion assays using Cefotaxime as a reference antibiotic; The antioxidant activity was carried out by three in vitro methods, the method of FRAP (ferro-reducing capacity), 2,2-diphenyl-1-picrylhydracil (DPPH) and 2,2'- azino-bis (3-ethylbenzothiazoline)-6-sulfonic (ABTS•+). The results obtained indicated that the analyzed extracts of both Malva species showed a moderate antibacterial activity in certain concentrations against the microorganisms E. coli,S. aureus and K. pneumoniae; and taking into account the results of the antioxidant activity in the three in vitro methods tested, it was I observed that as the concentration of the extracts increased, the reducing power (FRAP test) and the anti-radicals activity (DPPH and ABTS•+ tests) increased as well, manifesting a high antioxidant activity. As a consequence of this, we can conclude that Malva sylvestris and Malva pseudolavatera leaf extracts produce inhibition halos in the strains of the microorganisms evaluated (E. coli, S. aureus, K. pneumoniae), in addition to presenting inhibition of the radicals used (DPPH, ABTS•+) and ferro- reducing capacity (FRAP).