Cytoprotection of Cecropia obtusifolia Bertol (Cecropiaceae) extract on the normal adherent cell line of human fibroblasts Hs68

• Villarreal-Ibarra, Edelia Claudina ^[1] ; Rivas-Morales, Catalina ^[2] ; Leos-Rivas, Catalina ^[2] ; Rivera Hernández, Benigno ^[1] ; Almenares López, Damianys ^[1]
  1. [1] Universidad Popular de la Chontalpa

     Universidad Popular de la Chontalpa

     México

     
  2. [2] Universidad Autónoma de Nuevo León

     Universidad Autónoma de Nuevo León

     México

     
• Localización: Salud, Ciencia y Tecnología - Serie de Conferencias, ISSN-e 2953-4860, Vol. 3, Nº. 0, 2024 (Ejemplar dedicado a: Salud, Ciencia y Tecnología - Serie de Conferencias)
• Idioma: inglés
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• Resumen

  • The study focuses on the therapeutic action of medicinal plants used in the treatment of chronic degenerative diseases. The ethanolic extract of the Mexican species Cecropia obtusifolia Bertol, traditionally used for diabetes, was evaluated. The cytoprotective effect was determined on the normal adherent human fibroblast cell line Hs68, and its toxicity was assessed on Artemia salina. The cytoprotective effect was determined using the neutral red (NR) assay, demonstrating a viability of 98 %, indicating a very low cytotoxic effect and no toxicity on A. salina. These assays have been routinely employed as screening methods for natural extracts and pure compounds with potential therapeutic effects against cancer