Fenotipificación del antigeno diego(a) en la comunidad Aimara, ciudad de Gosen, Lima 2023 Phenotypification of the diego(a) antigen in the Aimara community, city of Gosen, Lima 2023

• Autores: Fernando Palacios, Rosa Gutiérrez, Evert Suarez, Carlos Gabriel, Dorian Miranda
• Localización: GICOS: Revista del Grupo de Investigaciones en Comunidad y Salud, ISSN-e 2610-797X, Vol. 9, Nº. 3 (septiembre-diciembre), 2024, págs. 39-53
• Idioma: español
• Títulos paralelos:
  • Phenotypification of the diego(a) antigen in the Aimara community, city of Gosen, Lima 2023
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  • español

    Objetivo: estimar la prevalencia del fenotipo Diego(a), y su relación con el grupo sanguíneo ABO/RH, género, edad y aloinmunización contra dicho antígeno en pobladores aimaras de ciudad de Gosen, Lima 2023. Método: estudio descriptivo, transversal, reclutándose 125 pobladores aimaras que fueron convocados en previa sensibilización e invitados individualmente o familiar, para fenotipificación del antígeno Diego(a) independientemente de edad, género. Resultados: se tipificaron 125 pobladores aimaras, de los cuales el 16.8% (21) presentaron el antígeno Diego(a), la relación con el sistema ABO, expresó una simultaneidad del antígeno Diego(a) y grupo O hasta en un 86.4%, seguido del A 8.8% y B con 4.8% respectivamente, en tanto con el sistema RH, todos fueron positivos (100%). Su distribución por género se encontró en varones 10.4% (n=21), y en femenino 6.4%, (n=21). Según los grupos etarios, resultó el mayor porcentaje en el grupo etario de 40 a más años 7.2% (n=9). La aloinmunización por transfusión representó el 0.8% y en razón a varones significa el 1.6%. Conclusiones: la prevalencia del antígeno Diego(a) en pobladores aimaras fue aproximadamente 17 de cada 100, se relacionó con el grupo O RH positivo, su presencia del antígeno Diego(a) fue mayor en varones; en edad mayores a 40 años y en relación a aloinmunización representó un muy bajo porcentaje según antecedente transfusional.ABSTRACTObjective: to estimate the prevalence of the Diego(a) phenotype, and its relationship with the ABO/RH blood group, gender, age and alloimmunization against said antigen in Aymara residents of the city of Gosen, Lima 2023. Method: descriptive, cross-sectional study, recruiting Aymara residents who were summoned in prior sensitization and invited individually or as a family, for phenotyping of the Diego(a) antigen regardless of age, gender, examining citrated whole blood and typing by microagglutination by Gel and recording in the blood phenotyping sheet. Results: 125 Aymara residents were typed, of which 16.8% (21) presented the Diego(a) antigen, the relationship with the ABO system, expressed a simultaneity of the Diego(a) antigen and group O in up to 86.4%, followed of A 8.8% and B with 4.8% respectively, while with the RH system, all were positive (100%). Its gender distribution was found in 10.4% males (n=21), and 6.4% females (n=21). According to the age groups, the highest percentage was in the age group of 40 or older, 7.2% (n=9). Alloimmunization by transfusion represented 0.8% and in terms of men it means 1.6%. Conclusions: the prevalence of the Diego(a) antigen in Aymara residents was approximately 17 out of every 100, it was related to group O RH positive, the presence of the Diego(a) antigen was greater in men; in age over 40 years and in relation to alloimmunization it represented a very low percentage according to transfusion history.Recibido: 10-05-2024Aprobado: 08-07-2024Publicado: 01-11-2024

  • English

    Objective: to estimate the prevalence of the Diego(a) phenotype, and its relationship with the ABO/RH blood group, gender, age and alloimmunization against said antigen in Aymara residents of the city of Gosen, Lima 2023. Method: descriptive, cross-sectional study, recruiting Aymara residents who were summoned in prior sensitization and invited individually or as a family, for phenotyping of the Diego(a) antigen regardless of age, gender, examining citrated whole blood and typing by microagglutination by Gel and recording in the blood phenotyping sheet. Results: 125 Aymara residents were typed, of which 16.8% (21) presented the Diego(a) antigen, the relationship with the ABO system, expressed a simultaneity of the Diego(a) antigen and group O in up to 86.4%, followed of A 8.8% and B with 4.8% respectively, while with the RH system, all were positive (100%). Its gender distribution was found in 10.4% males (n=21), and 6.4% females (n=21). According to the age groups, the highest percentage was in the age group of 40 or older, 7.2% (n=9). Alloimmunization by transfusion represented 0.8% and in terms of men it means 1.6%. Conclusions: the prevalence of the Diego(a) antigen in Aymara residents was approximately 17 out of every 100, it was related to group O RH positive, the presence of the Diego(a) antigen was greater in men; in age over 40 years and in relation to alloimmunization it represented a very low percentage according to transfusion history.