Histopatología de la pulpa de dientes de ratones sometidos a la acción de medicamentos utilizados en las terapias pulpares de dientes deciduos humanos

• Del Portillo Luján, Victor Augusto ^[1] ; Fazzi, Ronaldo ^[2] ; Guedes-Pinto, Antonio Carlos ^[2] ; Cavalcanti de Araújo, Vera
  1. [1] Universidad del Valle (Colombia)

     Universidad del Valle (Colombia)

     Colombia

     
  2. [2] Universidad de Sao Paulo. Brasil.
• Localización: Revista Estomatología, ISSN-e 2248-7220, Vol. 2, Nº. 1, 1992
• Idioma: español
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• Resumen

  • Histopatología de la Pulpa de Dientes de Ratones   Gerardo Umaña Resumen:En el presente trabajo se utilizaron 18 ratones (Wistar) distribuídos en 3 ratones por cada grupo experimental (24 horas, 3,7,14, 28 Y 90 días); estos animales fueron sometidos a una exposición pulpar, de los primeros molares superiores e inmediato recubrimiento con dos pastas a base de iodoformo, paramonoclorofeno alcanforado y Rifocort, además de hidróxido de calcio y óxido de zinc como productos modificadores en la pasta denominada como "experimental". Luego de los correspondientes procedimientos laboratoriales y obtención de los cortes histológicos para el estudio al microscopio de luz se pudo concluir que de una forma general las dos pastas son bien toleradas en el tejido conjuntivo de la pulpa de dientes de ratones. Revista Estomatología 1992; 2(1): 45-52.

      Summary:In this reseach 18 rats (wistar strain) were used divided in 3 animals for each experimental period of time previusly stabilited as 24 hours, 3, 7, 14, 28 and 90 days. In these animals a pulpal exposure was practicede the in upper firsc molais fllowed by imediat pulp capping with the paste being now proposed (experimental paste) or with one suggent by Guedes-Pinto &. Cols, 1981 (control paste). After the experimental times elapred the animals were sacfrificed and have their maxillae extracted for 7 um thick slides be made amd were dyed by means hematoxilin and eosin technique tobe examined at the ligtht miscroscope. From the histologic examination was posible to conlude tha both pastes were well tolerated by the conective pulpal tissue of the rat molars, sincea discreta inflatory reaction was found for time intervals of 24 hours and 3 days. For the 7 days observation period the initial formation of dentin bridge was seen that at op days was completely forme up to well as the periapical tissue have shown histologig characterristics of normality. The reseach has shown that the addition of calcium hydoxide and zinc oxide to the control paste did not modify the histo-pathoIogy reactions of rats pulpal tissue.