Premature Pubarche: A Pragmatic Approach

• Paul B. Kaplowitz ^[1]
  1. [1] Division of Endocrinology, Children's National Hospital, Washington, DC, USA
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 53, Nº. 2, 2024 (Ejemplar dedicado a: Precocious and Delayed Puberty Revisited), págs. 203-209
• Idioma: inglés
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• Resumen

  • Premature pubarche (PP) is a common and usually benign variant of normal puberty most often seen in 5-year-old to 9-year-old children. Some providers routinely order laboratory testing and a bone age to try to rule out other diagnoses including nonclassic congenital adrenal hyperplasia and gonadal or adrenal tumors. I review the natural history of PP and studies which suggest that without clinical features such as rapid growth and progression or genital enlargement, it is unlikely that a treatable condition will be found. Therefore it is recommended that patients with PP not undergo testing unless there are red flags at the time of the initial visit.