Evaluation of pan-immuno-inflammation value for in-hospital mortality in acute pulmonary embolism patients

• Vedat Çiçek ^[1] ; Samet Yavuz ^[3] ; Faysal Şaylık ^[4] ; Şölen Taşliçukur ^[5] ; Ahmet Öz ^[5] ; Mert Babaoğlu ^[3] ; Almina Erdem ^[3] ; İrem Yilmaz ^[3] ; Ulas Bagci ^[1] ; Tufan Çınar ^[2]
  1. [1] Northwestern University

     Northwestern University

     Township of Evanston, Estados Unidos

     
  2. [2] University of Maryland, College Park

     University of Maryland, College Park

     Estados Unidos

     
  3. [3] Department of Cardiology, Sultan II Abdulhamid Han Training and Research Hospital, Health Sciences University, Istanbul, Turkey
  4. [4] Department of Cardiology, Van Training and Research Hospital, Health Sciences University, Van, Turkey
  5. [5] Department of Cardiology, İstanbul Education and Research Hospital, İstanbul, Turkey

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• Localización: Revista de investigación clínica, ISSN 0034-8376, ISSN-e 2564-8896, Vol. 76, Nº. 2, 2024, págs. 97-102
• Idioma: inglés
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• Resumen

  • Pan-immuno-inflammation value is a new and comprehensive index that reflects both the immune response and systemic inflammation in the body. Objective: The aim of this study was to investigate the prognostic relevance of pan-immuno-inflammation value in predicting in-hospital mortality in acute pulmonary embolism patients and to compare it with the well-known risk scoring system, pulmonay embolism severity index, which is commonly used for a short-term mortality prediction in such patients. Methods: In total, 373 acute pulmonary embolism patients diagnosed with contrast-enhanced computed tomography were included in the study. Detailed cardiac evaluation of each patient was performed and pulmonary embolism severity index and pan-immuno-inflammation value were calculated. Results: In total, 60 patients died during their hospital stay. The multivariable logistic regression analysis revealed that baseline heart rate, N-terminal pro–B-type natriuretic peptide, lactate dehydrogenase, pan-immuno-inflammation value, and pulmonary embolism severity index were independent risk factors for in-hospital mortality in acute pulmonay embolism patients. When comparing with pulmonary embolism severity index, pan-immuno-inflammation value was non-inferior in terms of predicting the survival status in patients with acute pulmonay embolism. Conclusion: In our study, we found that the PIV was statistically significant in predicting in-hospital mortality in acute pulmonay embolism patients and was non-inferior to the pulmonary embolism severity index. (REV INVEST CLIN. 2024;76(2):97-102)