Resumen de Decarboxylation Pathways of Amino Acids in Some Mammal and Bird Tissues

John Claudatus, Pedro Gutierrez, Donald Lefemine

• español

  Los autores obtuvieron los siguientes resultados sobre la decarboxilación de aminoácidos en algunos tejidos homogenizados de mamíferos y aves. 1. RIÑÓN E HÍGADO DE CERDO: Fueron encontradas tres aminas prefor­madas y fuerte desaparición de la serotonina añadida, fuese por incubación aeró­bica o anaeróbica (fuertes conjugasas? y actividad de monoamino oxidasas). Después de incubación aeróbica y anaeróbica no se apreció desaparición de la histamina añadida. En el hígado la serotonina desapareció solamente des­pués de la incubación aeróbica. Se encontró glucosa libre (que reacciona con las aminas añadidas) en el hígado, pero no en el riñón. 2. SUPRARRENALES DE BUEY: Se encontraron dos componentes que parecen ser aminas y que no son noradrenalina ni dopamina. Hay ausencia de conjugasas y amino oxidasas. 3. HÍGADO DE COBAYO: Se observó fuerte desaparición de la serotonina añadida en incubaciones aeróbicas y anaeróbicas, al mismo tiempo que no se observó desaparición significativa de la histamina añadida en ninguna de las incubaciones, 4. HÍGADO DE Tarauco corythaix: Durante las incubaciones aeróbicas y anaeróbicas se observó fuerte desaparición de la serotonina añadida y muy leve, si no ninguna, desaparición de la histamina. 5. HÍGADO DE Cathartes aura septentrionalis: Se observó ausencia de metabolismo anaeróbico de serotonina y histamina añadidas (ausencia de con­jugasas?) Y marcada desaparición aeróbica de las dos aminas después de la incu­bación (fuerte actividad de mono y diamino oxidasas).

• English

  The following data were obtained on the decarboxylation pathways of amino acids in some mammal and bird tissue homogenates: 1. PIG KIDNEY AND LIVER: Three preformed amine-like compounds were observed in the kidney and strong disappearance of added serotonin during anaerobic and aerobic incubation (strong conjugases? and monoamine oxidase activities). No significant disappearance of added histamine was found after anaerobic or aerobic incubation. In the liver serotonin disappeared only after aerobic incubation. Free glucose (reacting with the added amines) was present in the liver but not in the kidney. 2. Ox ADRENALS: Two preformed amine-like compounds were present which are not noradrenalin or dopa amine. Absence of conjugases or amine oxidases. 3. GUINEA PIG LIVER; Strong disappearance of added serotonin after anaerobic incubation. No significant disappearance of added histamine in both types of incubations, 4. Tarauco corythaix LIVER: Strong anaerobic and aerobic disappearance of added serotonin and very slight if any disappearance of histamine in both types of incubation. 5. Cathartes ama septentrionalis (TURKEY BUZZARD) LIVER: Absence of anaerobic metabolism of added serotonin or histamine (absence of conju­gases?) and strong aerobic disappearance of both amines after incubation with both amines, (strong mono and diamine oxidase activities). The Eollowing data were obtained on the decarboxylation pathways oEamino acids in some mammaI and bird tissue homogenates:1 . P IG KIDNEY AND LIVER: Three preformed amine-like compounds wereobserved in the kidney and' strong disappearance oE added serotonin duringanaerobic and aerobic incubation (strong conjugases? and monoamine oxidaseactivities). No signiEicant disappearance of added histamine was found afteranaerobic or aerobic incubation.In the liver serotonin disappeared only after. aerobic incubation. Freeglucose (reacting with the added amines) was present in the l¡ver but not inthe kidney.2. Ox ADRENALS: Two preEormed amine-like compounds were presentwhich are not noradrenalin or dopa amine. Absence oE conjugases or amineoxidases.3. GUINEA PIe; UVER; Strong disappearance of added serotonin afterREVIs'rA DE ÍnOLOGIA TRÓPICAtanaerobic incubation. No significant dis:lppearance of addcd histaminc in bothtypcs of incubations,4. T arauco cOI'J'thclÍx L1VER: Strong anaerobic and aerobic disappearanceof added serotonin and very slight if any disappearance of histamine in bothtypes of incubation.5. CatiJartes ama Jeptentrionalü (TURKEY BUZZARD) UVER: Absenceof anaerobic metabolism of added serotonin or histamine (absence of conju­gases?) and strong aerobic disappearance of both amines after incubation withboth amines, (strong mono and diamine oxidase activities).