Improved statistical emulation for a soft-tissue cardiac mechanical model

• David Dalton ^[1] ; Dirk Husmeier
  1. [1] University of Glasgow

     University of Glasgow

     Reino Unido

     
• Localización: Proceedings of the 35th International Workshop on Statistical Modelling : July 20-24, 2020 Bilbao, Basque Country, Spain / Itziar Irigoien Garbizu (ed. lit.), Dae-Jin Lee (ed. lit.), Joaquín Martínez Minaya (ed. lit.), María Xosé Rodríguez Álvarez (ed. lit.), 2020, ISBN 978-84-1319-267-3, págs. 55-60
• Idioma: inglés
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• Resumen

  • This paper outlines a new approach to emulation based parameter inference in a cardiac mechanic model of the left ventricle (LV) of the heart that allows for prediction uncertainty to be accounted for. The emulation is performed using Gaussian processes, which are designed to build on the results of previous research in this area. This approach yields more accurate parameter estimates than previously reported in the literature.