Tensión de oxígeno y equilibrio ácido-base de madre y feto durante el parto en la altura
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[1] Universidad Peruana Cayetano Heredia
Universidad Peruana Cayetano Heredia
Perú
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- Localización: Revista Peruana de Ginecología y Obstetricia, ISSN-e 2304-5132, ISSN 2304-5124, Vol. 17, Nº. 1-2, 1971, págs. 45-66
- Idioma: español
- Títulos paralelos:
- Oxygen pressure and acid-base balance of mother and fetus during labor at high altitude
- Enlaces
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Resumen
- español
Quizás quisiste decir: The oxygen tensión and acid-bases status of mother and fetus have been studied at delivery in 12 subjects from Lima (150 m.] and Cerro de Pasco (4,200 ,m.), Perú. Despite the low pO2 (60.7 ± 2 mm.Hg., x ± SEM) of maternal arterial blood at altitude, the tension of oxygen measured in microsamples of arterialized capillary blood from the fetal scalp was similar at altitude (19.0 ± 1.16 mm.Hg.) and sea level (21.5 ± 1.12 mm.Hg.). The fetus at altitude is born with a mixed acid-base disturbance that combines a respiratory alcalosis (pCO2 = 29.8 ± 3.4 mm.Hg.) with a metabolic acidosis (base-excess = -7.4 ± 1.6 m.Eq./L) and a pH similar to that found at sea level. The low fetal pCO2 correlotes welI with a decreased maternal pC02, at altitude, due to the additive effects of the hyperventilations of altitude and pregnancy (r = 0.77, p < 0 .001). There is a high degree of correlation between the maternal pCO2 and the fetal base-excess (r = 0.73, p < 0.001). Our findings indicate that the neonate at altitude is frecuently "small for dates", with the corresponding risks of congenital malformations, hipoglicemia and pulmonary pathology. They will thus have on important meaning on the observed increase in neonatal mortality at altitude.El estado de la tensión de oxígeno y ácido-base de la madre y el feto se han estudiado en el parto en 12 sujetos de Lima (150 m.] Y Cerro de Pasco (4200, m.), Perú. A pesar de la baja pO2 (60,7 ± 2 mm. Hg., x ± SEM) de la sangre arterial materna en la altura, la tensión de oxígeno medido en micromuestras de sangre capilar arterializada del cuero cabelludo fetal fue similar en la altura (19,0 ± 1,16 mm Hg) y el nivel del mar (21,5 ± 1,12 mm .hg.). El feto en la altitud nace con una alteración ácido-base mixta que combina una alcalosis respiratoria (pCO2 = 29,8 ± 3,4 mm Hg) con una acidosis metabólica (base-exceso = -7,4 ± 1,6 m.eq ./L) y un pH similar al que se encuentra a nivel del mar. Las bajas fetales correlotes pCO2 weli con pC02 materna disminuyó, en altitud, debido a los efectos aditivos de los hiperventilations de altitud y el embarazo (r = 0,77, p <00,001). Existe un alto grado de correlación entre la pCO2 materna y la fetal base exceso (r = 0,73, p <0,001). Nuestros findinqs indican que el recién nacido en la altura es Frecuentes "pequeño para las fechas", con el correspondiente riesgos de malformaciones congénitas, hipoglicemia y la patología pulmonar. Por lo que tendrán un significado importante en el aumento observado en la mortalidad neonatal en la altura.
- English
The oxygen tensión and acid-bases status of mother and fetus have been studied at delivery in 12 subjects from Lima (150 m.] and Cerro de Pasco (4,200 ,m.), Perú. Despite the low pO2 (60.7 ± 2 mm.Hg., x ± SEM) of maternal arterial blood at altitude, the tension of oxygen measured in microsamples of arterialized capillary blood from the fetal scalp was similar at altitude (19.0 ± 1.16 mm.Hg.) and sea level (21.5 ± 1.12 mm.Hg.). The fetus at altitude is born with a mixed acid-base disturbance that combines a respiratory alcalosis (pCO2 = 29.8 ± 3.4 mm.Hg.) with a metabolic acidosis (base-excess = -7.4 ± 1.6 m.Eq./L) and a pH similar to that found at sea level. The low fetal pCO2 correlotes welI with a decreased maternal pC02, at altitude, due to the additive effects of the hiperventilations of altitude and pregnancy (r = 0.77, p < 0 .001). There is a high degree of correlation between the maternal pCO2 and the fetal base-excess (r = 0.73, p < 0.001). Our findinqs indicate that the neonate at altitude is frecuently "small for dates", with the corresponding risks of congenital malformations, hipoglicemia and pulmonary pathology. They will thus have on important meaning on the observed increase in neonatal mortality at altitude.
- español
