Biological screening of selected flora of Pakistan

• M Zia-Ul-Haq ^[1] ; M Raza Shah ^[2] ; Mughal Qayum ^[3] ; Sezai Ercisli ^[4]
  1. [1] University of Karachi Department of Pharmacognosy
  2. [2] University of Karachi International Center for Chemical and Biological Sciences H.E.J. Research Institute of Chemistry
  3. [3] Abdul Wali Khan University Department of Pharmacy
  4. [4] Ataturk University Department of Horticulture

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• Localización: Biological Research, ISSN-e 0717-6287, ISSN 0716-9760, Vol. 45, Nº. 4, 2012, págs. 375-379
• Idioma: inglés
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• Resumen

  • Methanolic extracts of different parts of five medicinal plants, Ferula assafoetidaL. resin, Grewia asiaticaL. leaves, Ipomoea hederaceaJacq. seeds, Lepidium sativumL. seeds and Terminalia chebulaRetz. fruits were tested in vitrofor their cytotoxic, phytotoxic, insecticidal, nematicidal and anthelmintic activities. Ipomoea hederaceashowed very significant phytotoxic and cytotoxic activity, with 100% inhibition of Lemna minorgrowth and 100% death of Artemia salinaat concentrations of 1000 and 100 µg mL-1. Grewia asiaticaexhibited very weak activities while Lepidium sativumand Ferula assafoetidashowed moderate to good potential in all three bioassays. The results suggest screening of Ipomoea hederaceaseeds further for isolation of bioactive compounds that may be responsible for its toxic potential.