Skin rash in a woman with hairy cell leukaemia

• Autores: Vitorino Modesto dos Santos, Gustavo Bettarello, Fernando Henrique de Paula, Rodrigo Aires de Castro, Eula Leisle Braz Lima, Thomas Edison Cintra Osterne
• Localización: Revista de la Facultad de Ciencias Médicas: (Quito), ISSN-e 2737-6141, ISSN 2588-0691, Vol. 34, Nº. 1-2, 2009 (Ejemplar dedicado a: Revista de la Facultad de Ciencias Médicas (Quito)), págs. 43-47
• Idioma: español
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• Resumen

  • Context: Skin eruptions associated with hairy cell leukaemia have been scarcely described.Case report: A 65-year-old woman with admission tests showing normal haemoglobin, severe neutropenia, and mild thrombocytopenia. The diagnosis of this leukaemia was based on typical hairy cells in bone marrow, in addition to immunohistochemistry, cell immunophenotype, and DBA4 marker. Administration of cladribine was followed by a generalized maculopapular rash and vesicles, which improved soon after the suspension of that drug.Conclusion: Skin eruptions associated to the use of cladribine occur in patients with hairy cell leukaemia, and may be underreported.