Resumen de Las Adverse drug reactions associated with the use of psychotropic drugs in pediatric patients with neurological disorders
- español
Objetivo: Analizar la prevalencia y causalidad de las reacciones adversas medicamentosas en pacientes pediátricos con desórdenes neurológicos. Métodos: Se realizó un estudio poblacional con 33 pacientes pediátricos, diagnosticados con desórdenes neurológicos y bajo tratamiento psicofarmacológico. Resultados: 48% de los pacientes presentaron reacciones adversas medicamentosas. Se detectaron 36 casos de reacciones adversas medicamentosas, de las cuales, la mayoría estuvieron relacionadas al uso de valproato de magnesio (39%), seguido de metilfenidato (22%), piracetam (17%) y topiramato (8%). Las principales reacciones adversas medicamentosas identificadas fueron: caries, hiperplasia, pérdida del apetito, gingivitis, hipersalivación, insomnio e irritabilidad.
- English
Objective: To identify and analyze the prevalence and causality of adverse drug reactions in pediatric patients with neurologic diseases. Methods: A population study was carried out with 33 pediatric patients diagnosed with neurologic diseases under treatment with psychoactive drugs. Results: 48 % of patients had adverse drug reactions. Thirty-six adverse events were identified, of which, most were associated to the use of magnesium valproate (39%), and followed by methylphenidate (22%), piracetam (17%), and topiramate (8%). The main identified adverse drug reactions were: caries, hyperplasia, loss of appetite, hypersalivation, insomnia and irritability.
