Susceptibilidad in vitro de cepas de Helicobacter pylori: aislamiento de cepas resistentes a claritromicina
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Carlos González C [1] ; Apolinaria García C ; Fabiola Daroch M ; Fernando Kawaguchi P ; Henry Solar R ; Nancy Rivera F ; Edith Vega C
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[1] Universidad de Concepción
Universidad de Concepción
Comuna de Concepción, Chile
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- Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 129, Nº. 6, 2001, págs. 643-646
- Idioma: español
- Títulos paralelos:
- In vitro antimicrobial susceptibility of Helicobacter pylori strains isolated in Chile
- Enlaces
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Resumen
Background: Our laboratory has carried out an epidemiological surveillance of Helicobacter pylori antimicrobial susceptibility since 1997. Aim: To report the antimicrobial susceptibility of H pylori strains, isolated in Chile from August 1997 to August 2000. Material and methods: Ninety one H pylori strains, obtained from antral gastric biopsies during upper gastrointestinal endoscopies were studied. Susceptibility towards clarithromycin, amoxicillin, bismuth subcitrate and metronidazole was studied by an agar diffusion technique. Results: All strains were susceptible to amoxicillin and two strains were resistant to clarithromycin. Forty two percent of strains were resistant to metronidazole and 13% were resistant to bismuth subcitrate. Conclusions: These results underscore the need to maintain an epidemiological surveillance of H pylori antimicrobial susceptibility, to modify its eradication therapy accordingly. (Rev Méd Chile 2000; 129; 643-6
