Comparación de susceptibilidad de especies de Shigella a antimicrobianos de uso habitual en el Hospital Regional de Temuco, Chile 1990-2001

• Cecilia Boehme K ^[1] ; Trinidad Iglesias S ^[1] ; Aurora Loyola M ^[1] ; Lilian Soto F ^[1] ; Gloria Rodríguez M ^[1] ; Patricia Reydet B ^[1] ; Vijna Illesca B ^[1]
  1. [1] Universidad de La Frontera

     Universidad de La Frontera

     Temuco, Chile

     
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 130, Nº. 9, 2002, págs. 1021-1026
• Idioma: español
• Títulos paralelos:
  • Shigella species susceptibility to commonly used antimicrobials in the Temuco Regional Hospital, Chile 1990-2001
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• Resumen

  • Background: The permanent surveillance of antimicrobial susceptibility of Shigella sp in the Temuco Regional Hospital, allowed us to define the empirical use of antimicrobials in dysenteric syndrome. Aim: To study antimicrobial susceptibility of Shigella strains collected from 1997 to May 2001 and compare the results with those reported in 1990. Material and methods: Two hundred and seventeen Shigella strains, coming from stool cultures of pediatric patients, were studied. Results: In the period 1989-1990 Shigella flexneri was the main species isolated (83%) whereas, in the period 1997-2001, Shigella sonnei (55.8%) predominated. In the second period, an increase of antimicrobial resistance, as compared with the period 1989-1990, was observed for ampicillin (74.5 and 42% respectively), for cotrimoxazol (57.5 and 45% respectively) and tetracycline (64 and 8% respectively). Chloramphenicol resistance increased from 0 to 57.5%. In the second period no resistance to ciprofloxacin was detected. There was simultaneous resistance to four drugs in 30% of the strains, predominating multiresistance in S flexneri (52.1%). Conclusions: In the two periods studied, a significant increase was detected in the resistance of Shigella strains to antimicrobials (Rev Méd Chile 2002; 130: 1021-6).