Síndrome de Turner: Crecimiento y descripción clínica en 83 niñas chilenas

• Rossana Román ^[1] ; María Eliana Vallejos ^[1] ; Mónica Muñoz ^[3] ; Ruth Schneider ^[1] ; Ronald Youlton ^[2] ; Cecilia Henriquez ^[1] ; Fernando Cassorla ^[1]
  1. [1] Universidad de Chile

     Universidad de Chile

     Santiago, Chile

     
  2. [2] Clínica Las Condes

     Clínica Las Condes

     Santiago, Chile

     
  3. [3] Hospital Calvo Mackenna

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• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 130, Nº. 9, 2002, págs. 977-984
• Idioma: español
• Títulos paralelos:
  • Spontaneous growth of 83 Chilean girls with Turner's syndrome
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• Resumen

  • Background: Short stature is the main feature of patients with Turner's syndrome. There is limited information regarding the spontaneous growth of these patients in Chile. Aim: To develop a specific growth chart for Chilean patients with Turner's syndrome. Material and methods: We retrospectively analyzed 668 height measurements from 85 Chilean girls, born after 1968, with 45XO karyotype (minimum 15%), and without an Y chromosome fragment. Patients with hormonal therapy, such as growth hormone or estrogen, except thyroid hormone replacement, were excluded. Results: The karyotypes were 60% 45XO, 25% 45XO, 46XX, and 15% other complex mosaics. The birth length was 46.8 ± 2.1 cm. The final height of our patients was 138,20 ± 7,0 cm. Conclusions: The final height achieved by our patients, is similar to Argentinian and Japanese patients, but is below the mean stature reported for Scandinavian and Northamerican patients who achieve a mean adult height of approximately 147 and 142 cm respectively. The birth length is also lower than that reported in those studies (Rev Méd Chile 2002; 130: 977-84).