With this issue, Revista Médica de Chile will have been published uninterruptedly, for 130 years. Formal medical education had an early development since Chile became independent from Spain (1817). The first Medical Sciences Course was organized in 1833 by the Irish physician William C Blest. The Santiago Medical Society was founded in 1869 and its journal -Revista Médica de Chile- in 1872. Its first director was Dr. German Schneider. Revista Medica is the oldest serial publication in South America and the second oldest in the Spanish speaking world. This is a remarkable fact for a comparatively young country. With the creation of the Medical Society and Revista Medica, a process of continuous medical education was started and they became a real Graduate School. The Journal has adopted the main changes in knowledge and technology. Some important milestones of its development, during the second half of the 20th century, were the definition of its objectives and structure, the incorporation of peer review of manuscripts (even with foreign reviewers) the adoption of international guidelines for publication, its incorporation into the main biomedical journal indexes, the modernization of its printing process, the making of a computer generated index of all papers published since 1872, its incorporation into a digital library in INTERNET and the active participation of its editors in the World Association of Medical Journal Editors. The success of the journal is influenced by the independence that the Medical Society has conferred to the editors (all outstanding University Professors), as well as to the characteristics of an educational campus "invisible and without tumult" (Ingelfinger) (Rev Méd Chile 2002; 130: 719-22)
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