Tratamiento del estado epiléptico refractario con topiramato oral

• Bernardita Soler ^[1] ; Jaime Godoy ^[1] ; Patricio Mellado ^[1]
  1. [1] Pontificia Universidad Católica de Chile

     Pontificia Universidad Católica de Chile

     Santiago, Chile

     
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 137, Nº. 7, 2009, págs. 936-939
• Idioma: español
• Títulos paralelos:
  • Treatment of refractory status epilepticus with topiramate. Report of three cases
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• Resumen

  • Refractory status epilepticus is a catastrophic illness of the central nervous system, with a mortality rate that reaches 50%. We report three patients admitted with refractory status epilepticus: a 24 year-old male that discontinued antiepileptic medications, a 46 year-old male with a focal epilepsy secondary to an encephalitis that discontinued medications due to gastrointestinal problems and a 59 year-old male with an ischemic encephalopathy AH were treated with topiramate, delivered through a nasogastric tube with a good response.