Staphylococcus aureus comunitario resistente a cloxacilina: Comunicación de los primeros cinco casos descritos en Chile

• Luis Miguel Noriega ^[1] ; Patricia González ^[1] ; Juan Carlos Hormazábal ^[2] ; Consuelo Pinto ; Magdalena Canals ; José Manuel Munita ^[1] ; Luis Thompson ^[1] ; Alejandra Marcotti ^[1] ; Jorge Pérez ^[1] ; Daniel Ibáñez ^[2] ; Pamela Araya ^[2] ; Claudio Canals ^[1] ; Pablo Vial ^[1]
  1. [1] Clínica Alemana

     Clínica Alemana

     Santiago, Chile

     
  2. [2] Instituto de Salud Pública Subdepartamento de Microbiología Clínica
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 136, Nº. 7, 2008, págs. 885-891
• Idioma: español
• Títulos paralelos:
  • Community acquired infections with methicillin resistant strains of Staphylococcus aureus: Report of five cases
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• Resumen

  • Community acquired infections with methicillin resistant strains of Staphylococcus aureus (MRSA) infections have a more aggresive clinical course and involve mostly skin and lungs. These infections appear as outbreaks among prisoners, spoñsmen, men having sex with men and military personnel. The higher aggressiveness of these strains is due to the production of several toxins, mainly Panton- Valentine leukocidine. The detection of the gene that codes for this toxin is a distinctive feature ofthese strains. We report five patients with community acquired MRSA infections. The clinicalpresentation was a skin infection in all. One patient had a pleuropneumonia in addition. Apart for resistance to beta-lactam antimicrobials, the strains were resistant to erythromycin and ciprofloxacin. Patients were treated with vancomycin, clotrimoxazole or intravenous clindamycin with a good evolution. An epidemiológical surveillance for community acquired MRSA strain infections should be started and measures to adequately treat infected patients and avoid dissemination should be implemented