Carcinoma hepatocelular variedad fibrolamelar metastásico en menores de 20 años: Reporte de 2 casos tratados con intención curativa y revisión de la literatura

• Jean M Butte ^[2] ; Enrique Waugh ^[2] ; Manuel Meneses ^[2] ; Rossana Pruzzo ^[2] ; Cristian Carvallo ^[1] ; Francisca Redondo ^[2] ; Claudio Suárez ^[1] ; Hugo Parada ^[2] ; Horacio Amaral ^[2] ; Hernán de La Fuente ^[2]
  1. [1] Clinica Santa Maria

     Clinica Santa Maria

     Santiago, Chile

     
  2. [2] Instituto Oncológico Fundación Arturo López Pérez
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 137, Nº. 3, 2009, págs. 394-400
• Idioma: español
• Títulos paralelos:
  • Fibrolamellar liver carcinoma: Report of two cases
• Enlaces
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• Resumen

  • Fibrolamellar hepatocellular carcinoma (FLC) is a rare histologic variant of hepatocellular carcinoma that appears most commonly in teenagers andyoung adults. The diagnosis is often made incidentally and surgical resection is the only curative treatment. Here we report two cases of incidental FLC involving a 19 year-old male, initially diagnosed with screening abdominal ultrasound, and a 14 year-old female that presented with abdominalpain. Diagnostic workup consisted of abdominal PET/CT and MR1Imaging studies and tissue diagnosis was confirmed with percutaneous liver biopsy. Both patients were treated with radical liver resection/tumor excision. However, tumor recurrence was observed in both during short-term follow-up. The male patient was treated successfully with surgical treatment however the female patient succumbed top regression of disease.