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Resumen de Primer trasplante de intestino en Chile: Caso clínico

Erwin Buckel G, Mario Ferrario B, Mario Uribe M, Gloria González G, Jorge Godoy L, Fernando Fluxá, Rodrigo Quera P, Verner Codoceo, Jorge Morales B, David Benavente M, María Teresa Santander D, Cristina Herzog

  • Small bowel transplantation is associated with a patient survival at one and five years, of 80% and 63%, respectively. We repon a 36 year-old female with short bowel syndrome, subjected to the first small bowel transplantation performed in Chile. A cadaveric gran was used. Immunosuppression was achieved by means of alemtuzumab, tacrolimus, sirolimus, micofenolate mofetil and steroids. Serial endoscopies and biopsies were performed during seven months after transplantation. The most important ¡ate complications were a drug induced renal failure, infections caused by opportunistic agents and a gastrointestinal bleedingprobably induced by drugs. After 29 months of follow up, the patient is ambulatory, on oral diet only and with no evidence of graft rejection.


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