Glomerulopatia colapsante

• Juan Carlos Said ^[1] ; Luz María Letelier ^[2] ; Alejandro González ^[2] ; Cristóbal Escobillana ^[3] ; Raúl Pisano ^[1]
  1. [1] Hospital San Juan de Dios

     Hospital San Juan de Dios

     Santiago, Chile

     
  2. [2] Hospital Dr. Sótero del Río Departamento de Medicina Interna y Unidad Docente Asociada
  3. [3] Hospital Dr. Sótero del Río Servicio de Nefrologia

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• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 140, Nº. 10, 2012, págs. 1342-1346
• Idioma: español
• Títulos paralelos:
  • Collapsing glomerulopathy
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• Resumen

  • Background: Collapsing glomerulopathy is a cause of nephrotic syndrome with massive proteinuria secondary to podocyte proliferation and glomerular collapse. It is characterized by an almost inevitable progression to end stage renal failure, poor response to treatment and high post-transplant recurrence. Its frequency has increased in recent years due to its common association with Human Immunodeficiency Virus (HIV) infection and the growing recognition of new etiologic agents such as drugs and parvovirus B19. Therefore, it is a disease of growing interest for clinicians. The aim of this review is to update the clinical presentation, diagnosis, pathogenesis and therapeutic alternatives of this disease.