Rememorando la contribución de Goldstein y Brown al estudio del metabolismo del colesterol: a un cuarto de siglo del Premio Nobel de Medicina

• Víctor Cortés ^[1] ; Tatiana Vásquez ^[1] ; Antonio Arteaga ^[1] ; Flavio Nervi ^[2] ; Attilio Rigotti ^[1]
  1. [1] Pontificia Universidad Católica Departamentos de Nutrición, Diabetes y Metabolismo Escuela de Medicina
  2. [2] Pontificia Universidad Católica Departamento de Gastroenterología Escuela de Medicina
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 140, Nº. 8, 2012, págs. 1053-1059
• Idioma: español
• Títulos paralelos:
  • The contribution of Goldstein and Brown to the study of cholesterol metabolism
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• Resumen

  • Background: In December 1985, the Nobel Prize of Medicine was awarded to Drs. Joseph L. Goldstein and Michael S. Brown for their fundamental scientific work on the regulation of cholesterol metabolism mediated by the low density lipoprotein receptor pathway. This article briefly reviews the academic and research accomplishments of Drs. Brown and Goldstein as a tribute to these physician-scientists for their well-deserved award and enormous contribution to biomedical science worldwide.