Grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicos

• Paola Varleta ^[1] ; Roberto Concepción ^[1] ; Patricio Vargas ^[2] ; Héctor Casanova ^[3]
  1. [1] Hospital de Carabineros

     Hospital de Carabineros

     Santiago, Chile

     
  2. [2] Universidad del Desarrollo

     Universidad del Desarrollo

     Santiago, Chile

     
  3. [3] Dirección de Previsión Carabineros de Chile Medicina Preventiva Carabineros de Chile

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• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 141, Nº. 6, 2013
• Idioma: español
• Títulos paralelos:
  • Association of carotid intima-media thickness with traditional cardiovascular risk and metabolic factors
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• Resumen

  • Background: Carotid intima-media thickness (IMT) is a surrogate marker of subclinical atherosderosis and is associated with cardiovascular risk factors (CVRF) Aim: To analyze the association of CVRF and metabolic factors (MF) with IMT, and if the clustering of these factors modify IMT. Material and Methods: Cross sectional study in 187 participants aged 46±10years (53% male) without CV disease. Weight, height, waist circumference (WC), blood pressure, fasting plasma glucose and lipid profile were measured. Abdominal obesity (AOb) was defined by ATP III criteria. Mean carotid IMT was measured at the farwall of the common carotid artery. The cutoff point for an abnormally high IMT was set at the 75th IMT percentile of the sample. Results: The 75th IMT percentile of the sample was 0.67 mm. In a multivariate analysis four factors were significantly related with a high IMT: age (odds ratio (OR): 5.3, confidence intervals (CI): 2.2-12.9), dyslipidemia (OR: 6.4 CI: 2.3-17.9), systolic blood pressure (OR: 2.9, CI: 1.2-7.1) and AOb (OR: 2.9 (IC: 1.1-7.2). The presence of Oto 4 of these factors was associated with an IMT increment from 0.54 to 0.71 mm (p < 0,001). Conclusions: In this sample dyslipidemia, systolic blood pressure and abdominal obesity were the main predictors of a high IMT.