Enfermedad de Von Economo: Caso clínico

• Sabrina F Vadalá ^[1] ; Débora Pellegrini ^[1] ; Emanuel D Silva ^[1] ; Diego Miñarro ^[1] ; Bárbara C Finn ^[1] ; Julio E Bruetman ^[1] ; Gabriel Nápoli ^[1] ; Pablo Young ^[1]
  1. [1] Hospital Británico de Buenos Aires

     Hospital Británico de Buenos Aires

     Argentina

     
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 141, Nº. 4, 2013, págs. 531-534
• Idioma: español
• Títulos paralelos:
  • Lethargic Encephalitis: Report of one case
• Enlaces
  • Texto completo
• Resumen

  • Lethargic encephalitis (LE) is a Central Nervous System disorder following an upper respiratory tract infection, characterized by sleep disturbances, clinical symptoms corresponding to basal ganglia involvement and in some cases, neuropsychiatric sequelae. We report a 18-year-old mole with a history of sinusitis treated with azithromycin, two weeks before, presenting with fever, headache, confusion and myoclonus. Urine analysis was positive for cannabis. Cerebro spinal fluid analysis showed mononuclear pleiocytosis (109xmm³) and an increase in protein concentration ofl.6 g/dl. Forty eight hours after admission, the patient required mechanical ventilation and subsequently a status epilepticus appeared. Ten days later, fever, rigidity and resting tremor appeared. A magnetic resonance imaging showed hyperintensities in FLALR sequence in the right insular cortex. The patient continued with extreme rigidity, catatonia and mutism. Considering the possibility ofa LE, methyl prednisolone 1 g/day was administered for five consecutive days followed by prednisone 40 mgl day, observing a dramatic improvement of rigidity and tremors.