Ayuda
Ir al contenido

Dialnet


Resumen de Asociación entre obesidad y cáncer de ovario

Macarena Valladares Vega, Gino Corsini, Carmen Romero

  • Obesity is a risk factor for cancer. Epidemiological evidences associate ovarian cancer with obesity. Epithelial ovarian cancer (EOC) is the most common type of ovarian cancer and accounts for a high rate of mortality. The association between ovarian cancer and obesity could be explained by molecular factors secreted by adipose tissue such as leptin. In EOC, leptin increases cell proliferation and inhibits apoptosis. Additionally, adipose tissue synthesizes endogenous estrogens, which increase cell proliferation of epithelial ovarian cells. Also, obesity associated hyperinsulinism could increase ovarian estrogen secretion.


Fundación Dialnet

Dialnet Plus

  • Más información sobre Dialnet Plus