Vasculitis de grandes vasos en paciente con vasculitis ANCA (+): Caso clínico

• Jorge Vega ^[2] ; Francisco J Guarda ^[1]
  1. [1] Pontificia Universidad Católica de Chile

     Pontificia Universidad Católica de Chile

     Santiago, Chile

     
  2. [2] Hospital Naval A. Nef Sección Nefrología Servicio de Medicina
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 143, Nº. 9, 2015, págs. 1206-1209
• Idioma: español
• Títulos paralelos:
  • Large vessel involvement in ANCA-associated vasculitis: Report of one case
• Enlaces
  • Texto completo
• Resumen

  • Pauci-immune glomerulonephritis in systemic vasculitides usually have anti-neuthrophil cytoplasmic antibodies (ANCA). However, vasculitides of large vessels such as Takayasu’s and giant cell (temporal) arteritis do not. Exceptionally ANCA(+) small vessel vasculitides are associated with large vessel vasculitis. It may be a coincidence or both vasculitides have a common pathogenesis. We report a 30 years old woman on hemodialysis due to a chronic glomerulonephritis ANCA(+) diagnosed nine years ago. Eight years later, she presented with an aortitis with severe stenosis of distal aorta and vasculitis of left subclavian artery. She was treated with adrenal steroids and cyclophosphamide. During the ensuing five years she has been stable and without signs of reactivation of the disease.