Linfoma intravascular, un desafio diagnóstico: Caso clínico

• Pablo Young ^[1] ; María Massa ^[1] ; Bárbara C Finn ^[1] ; Gonzalo Fleire ^[1] ; Germán R Stemmelin ^[2] ; Amanda Ruades ^[2] ; Daniel Sutovsky ^[2] ; José G Casas ^[3] ; Pablo Dezanzo ^[3] ; Félix Vigovich ^[3] ; Julio E Bruetman ^[1]
  1. [1] Hospital Británico

     Hospital Británico

     Uruguay

     
  2. [2] Hospital Británico Servicio de Hematología
  3. [3] Hospital Británico Servicio de Histopatología

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• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 143, Nº. 8, 2015, págs. 1076-1080
• Idioma: español
• Títulos paralelos:
  • Intravascular lymphoma: Report of one case
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• Resumen

  • Intravascular lymphoma is a rare subtype of extranodal diffuse large B-cell lymphoma characterized by clonal proliferation of lymphocytes inside of small and medium caliber vessels. Its incidence is estimated at one case per million. The clinical picture is very variable, but frequently has skin and central nervous system involvement. It is diagnosed by demonstrating pathological blood vessel infiltration by lymphoma cells. We report a 44 years old male presenting with fever, malaise and erythematous lesions in the abdominal wall. An abdominal wall biopsy showed dilated vascular vessels with atypical cells in their lumen, compatible with large B-cell intravascular lymphoma. He was treated with rituximab, cyclophosphamide, adriamycin, vincristine and prednisone and an autologous hematopoietic stem cell transplantation, achieving a complete remission that has lasted two years.