Prueba de basculación (Tilt Table Testing): Comparación de dos protocolos: isoproterenol versus nitroglicerina

Pedro Jiménez-Cohl ^[2] ; Sebastián Vega ^[1] ; Rocío Cáceres ^[1] ; Constanza Gómez ^[1] ; Nadia Rojas ^[1]
1. [1] Universidad de Valparaíso
  
  Universidad de Valparaíso
  
  Valparaíso, Chile
2. [2] Hospital Militar Servicio de Neurología Unidad de Estudios Autonómicos
Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 143, Nº. 1, 2015, págs. 69-76
Idioma: español
Títulos paralelos:
- Comparison of the use of isoproterenol or nitroglycerine during the Tilt test
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Resumen
- Background: There is debate about the advantages of different protocols usefulness of tilt test for the diagnosis of vasovagal collapse. Aim: To compare the sensitivity, specificity, adverse reactions, complications and time requirements of two different Tilt test protocols. Material and Methods: A Tilt test using isoproterenol in progressive doses (2 μg for 10 min and 5 μg for 5 min posteriorly was performed in 159 patients aged 9 to 84 years (59 males). Another Tilt test using sublingual nitroglycerine in doses of 0.3 mg was performed in 201 patients aged 8 to 87 years (62 males). Also, 20 healthy volunteers were tested. Results: The positivity rates of the tests using isoproterenol and nitroglycerin were 75.5 and 77.6% respectively (NS). The figures for sensitivity were 98.4 and 99.3% (NS). The figures for specificity were 93.2 and 98.4% (NS). The test using isoproterenol requires 15 more minutes. As adverse reactions, 38% of participants experienced palpitations with isoproterenol and 22% experienced headache with nitroglycerin. Conclusions: The Tilt test with nitroglycerin is shorter, simpler, painless, with less personnel involved and has the same diagnostic accuracy than the test with isoproterenol.