Neumonía intersticial inducida por bloqueo androgénico máximo como tratamiento de cáncer de próstata avanzado: Report of one case

• Guillermo Molina Mancero ^[1] ; Xavier Picón ^[1] ; Fernando Di Tullio ^[1] ; Glenda Ernst ^[1] ; Pablo Dezanzo ^[1] ; Alejandro Salvado ^[1] ; Julio F Chertcoff ^[1]
  1. [1] Hospital Británico de Buenos Aires

     Hospital Británico de Buenos Aires

     Argentina

     
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 144, Nº. 10, 2016, págs. 1356-1359
• Idioma: español
• Títulos paralelos:
  • Fatal interstitial lung disease associated with maximum androgen blockade
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• Resumen

  • Maximum androgen blockade is the standard endocrine treatment for advanced prostate cancer. Interstitial lung disease in different degrees of severity, with low mortality and excellent response to treatment may appear with its use. We report a 77 years old patient with advanced prostate cancer who developed severe and progressive respiratory failure associated to bilateral pulmonary infiltrates, attributed to the direct effect of maximum androgen blockade. Despite the therapeutic efforts, the patient died. Lung pathology revealed Usual Interstitial Pneumonia.