Determinación de la reserva ovárica mediante el recuento de folículos antrales en mujeres en edad reproductiva

• Autores: Joaquín Errázuriz V., Álvaro Carrasco, Elisa Díaz R., Pablo Sanhueza R., Patricio González S., Patricio Donoso P.
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 145, Nº. 6, 2017, págs. 741-746
• Idioma: español
• Títulos paralelos:
  • Association between antral follicle count and age in fertile women
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• Resumen

  • Background: Age plays a crucial role in women fertility and is related with a decreased oocyte quality and quantity. The evidence for this asseveration comes from data obtained in infertile women. However there is a paucity of studies in patients with proven fertility evaluating ovarian reserve and its decline with time. Aim: To measure antral follicle count (AFC) in probed fertile patients and to create a distribution chart based on variables that may affect its natural decline. Material and Methods: Observational prospective study. A transvaginal ultrasound was made between menstrual cycle days 3 and 5, evaluating AFC in 100 patients, followed during a year. Results: Median antral follicle count media was 14.5 (interval 3 to 26). There was a lineal decline of AFC with age. Women with hypertension and type 2 diabetes mellitus had significantly less follicles. However, a multiple regression analysis showed that only women's age was a significant predictor of AFC (R2 = 0.84). Conclusions: There was a lineal relationship between AFC and age in women with probed fertility.