Papel del médico de familia en el diagnóstico concomitante de mieloma y amiloidosis primaria en una misma paciente. Caso clínico

• Autores: F. Andrea Rodríguez-Lagos, José V. Sorlí, Michelle Cristina Calviño Naveira, Nuria Estañ Capell
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 146, Nº. 11, 2018, págs. 1351-1355
• Idioma: español
• Títulos paralelos:
  • Multiple myeloma associated with a secondary amyloidosis. Report of one case
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• Resumen

  • Multiple Myeloma is a myeloproliferative disorder of plasma cells, which may be complicated with secondary amyloidosis. We report a 48 year old woman consulting to primary care for weight loss and malaise. An initial laboratory study revealed a hypogammaglobulinemia with a monoclonal component and lambda light chains. These results motivated her derivation to hematology: her serum calcium was 11.8 mg/dl, immunofluorescence showed a monoclonal component of lambda chains and urine Bence-Jones protein was positive. A bone marrow biopsy confirmed plasma cell infiltration. A Congo-red stain of a rectal biopsy was positive. The patient was treated with thalidomide, bortezomid and dexamethasone.