Hierro intravenoso en la terapia del síndrome de piernas inquietas

• Autores: Marcelo Miranda C., María Leonor Bustamante
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 147, Nº. 12, 2019, págs. 1569-1571
• Idioma: español
• Títulos paralelos:
  • Intravenous iron for restless legs syndrome. Report of five cases
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• Resumen

  • Restless legs syndrome (RLS) may severely affect the quality of life of patients. A deficient iron incorporation into the central nervous system has an important role in the pathophysiology of RLS. Severely affected patients may not respond to current therapeutic options. We report a preliminary experience with five patients with severe RLS and low serum ferritin levels who did not improve with oral iron. All were treated with 1 g of intravenous iron carboxymaltose. They experienced a marked improvement in symptoms, evident even during the first week of therapy that had persistent after up to two years of follow-up. A significant change in the RLS severity scale was observed after intravenous iron. Serum ferritin levels increased in all of them. Intravenous iron could be a therapeutic option for patients with severe RLS.