The preparation of oxygenated derivatives of ambrox and isoambrox from drimenol

• JULIO BENITES ^[1] ; JOSE LOPEZ ^[1] ; JORGE G. FARIAS ^[1] ; MANUEL CORTES ^[2]
  1. [1] Universidad Arturo Prat

     Universidad Arturo Prat

     Iquique, Chile

     
  2. [2] Pontificia Universidad Católica de Chile

     Pontificia Universidad Católica de Chile

     Santiago, Chile

     
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 51, Nº. 3, 2006, págs. 979-981
• Idioma: inglés
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• Resumen

  • The preparation of oxygenated derivatives of ambrox and isoambrox is described. The compounds 8á-hydroxy-isoambrox, 7β-hydroxy-isoambrox, 8á-hydroxy-ambrox, 7β-hydroxy-ambrox, 7-oxo-isoambrox and 7-oxo-ambrox have been synthesized from (-)-drimenol, readily available from the bark of Drimys winteri. The structures of the products were determined mainly by spectroscopic methods