Magnetic behavior and antibacterial activity of iron (iii) complexes

• PIEDAD CORTÉS-CORTÉS ^[1] ; ANA MARÍA ATRIA ^[1] ; MARTÍN CONTRERAS ^[1] ; OCTAVIO PEÑA ^[3] ; KATIA FERNÁNDEZ ^[2] ; GINO CORSINI ^[2]
  1. [1] Universidad de Chile

     Universidad de Chile

     Santiago, Chile

     
  2. [2] Universidad Diego Portales

     Universidad Diego Portales

     Santiago, Chile

     
  3. [3] Université de Rennes I Institut de Chimie de Rennes

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• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 53, Nº. 2, 2008, págs. 1527-1532
• Idioma: inglés
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• Resumen

  • The preparation, magnetic characterization and antimicrobial properties of the complexes [Fe(3)0(CH3COO)6(CH3COOH)(H(2)0)]Cl(MeImid)-(H(2)0) (1) and [Fe(4)0(2)(CH3COO)(7)0(2)(BPA)2(H(2)0)]- CH.25(CH3CH2OH)(H(2)0) (2), where Melmid is 2-methyl-imidazolium and BPA is 2,2'-bipyridine, are described. The variable temperature susceptibilities of these complexes were investigated in the temperature range 2-300K. The data have been modeled on the assumption of "butterfly" arranged for (2) and equilateral triangle of ferric ions for (1). The antimicrobial activities of these complexes have been screened in vitro against different bacterial strains. The complexes (1) and (2) display activity over Gram negative bacteria and these compounds not present activity over Gram positive strains. These complexes have bacteriostatic effect over bacterial target. The toxicity analyses of iron complexes showed these have cytotoxicity effect to values around the MIC on human cell.