Resumen de Carbon-based solid acid catalyzed synthesis of polyhydroquinoline derivatives via hantzsch reaction under solvent-free conditions
Abolghasem Davoodnia, Amir Khojastehnezhad
An easy method for the synthesis of polyhydroquinoline derivatives via one-pot four-component Hantzsch condensation of dimedone, aryl aldehydes, ethyl acetoacetate and ammonium acetate in the presence of a catalytic amount of carbon-based solid acid (CBSA) in solvent-free conditions is described. The main advantages of the present approach are relatively short reaction times, high product yields, clean reaction profiles, simple experimental and work-up procedure.
