Solvent-free c-alkylation of barbituric acid in the nanocrystalline mordenite media

• GHOLAMHASSAN IMANZADEH ^[1] ; SAEED KABIRI ^[1] ; SAEED TAGHAVI ^[1] ; MOHAMMADREZA ZAMANLOO ^[1] ; YAGOUB MANSOORI ^[1]
  1. [1] University of Mohaghegh Ardabili College of Science Department of Chemistry
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 58, Nº. 3, 2013, págs. 1888-1891
• Idioma: inglés
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• Resumen

  • A simple, efficient and clean procedure has been developed for the C-alkylation of barbituric acid. The Michael addition of barbituric acid to α,β-unsaturated esters by employing K2CO3 in the nano-mordenite media (K2CO3/nano-MOR), as catalyst, gave C-alkylated barbituric acid in good to excellent yield. Nano-MOR showed good reusability. K2CO3/nano-MOR catalyst has been found to be an excellent catalyst for the reaction under solvent-free conditions at 80-90 °C.