Synthesis of 4-thiazolidine derivatives of 6-nitroindazole: Pharmaceutical importance

• PUSHKAL SAMADHIYA ^[1] ; RITU SHARMA ^[1] ; SANTOSH K SRIVASTAV ^[1] ; SAVITRI D SRIVASTAVA ^[1]
  1. [1] Dr. H.S. Gour University Department of Chemistry
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 57, Nº. 1, 2012, págs. 1036-1043
• Idioma: inglés
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• Resumen

  • New series of N-[3-(1H-6-nitroindazol-1-yl)-propyl]-2-(substituted phenyl)-4-oxo-5-(substituted benzylidene)-1,3-thiazolidine-carboxamide, compounds 5(a-j) have been synthesized from 6-nitroindazole. Structures of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR, ¹H NMR, 13C NMR and FAB-Mass. All the synthesized compounds were screened for their antibacterial, antifungal, antitubercular and antiinflammatory activities.