New azo-schiff base derived with ni(ii), co(ii), cu(ii), pd(ii) and pt(ii) complexes: Preparation, spectroscopic investigation, structural studies and biological activity

• ABBAS ALI SALIH AL-HAMDANI ^[1] ; ABDEL MAJID BALKHI ^[2] ; AHMAD FALAH ^[2] ; SHAYMA A SHAKER ^[3]
  1. [1] University of Baghdad College of Science for Women Department of Chemistry
  2. [2] University of Damascus Faculty of Science Department of Chemistry
  3. [3] komar University of Science and technology Departament of enviromental engineering

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• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 60, Nº. 1, 2015, págs. 2774-2785
• Idioma: inglés
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  • The coordination ability of the azo-Schiff base 2-[1,5-Dimethyl-3-[2-(5-methyl-1H-indol-3-yl)-ethyl imino]-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylazo]-5-hydroxy-benzoic acid has been proven in complexation reactions with Co(II), Ni(II), Cu(II), Pd(II) and Pt(II) ions. The free ligand (LH) and its complexes were characterized using elemental analysis, determination of metal concentration, magnetic susceptibility, molar conductivity, FTIR, Uv-Vis, (1H, 13C) NMR spectra, mass spectra and thermal analysis (TGA). The results confirmed the coordination of the ligand through the nitrogen of the azomethine, Azo group (Azo) and the carboxylate ion with the metal ions. The activation thermodynamic parameters, such as ΔE*, ΔH*, ΔS*, ΔG*and K are calculated from the TGA curves using Coats-Redfern method. Hyper Chem-8 program has been used to predict structural geometries of compounds in the gas phase. The synthesized ligands and their metal complexes were screened for their biological activity against bacterial species, two Gram positive bacteria (Bacillus subtillis and Staphylococcus aureus) and two Gram negative bacteria (Escherichia coli and Pseudomonas aereuguinosa).