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Resumen de Mathematical Modelling of HIV/AIDS Treatment Using Caputo–Fabrizio Fractional Differential Systems

S. Manikandan, T. Gunasekar, A. Kouidere, K.A. Venkatesan, Kamal Shah, Thabet Abdeljawad

  • The focus of this study lies in developing and evaluating a Caputo–Fabrizio fractional derivative model that encapsulates the dynamics of the worldwide HIV/AIDS epidemic while integrating an antiretroviral therapy component. The methodology involves employing iterative techniques alongside the fixed-point theorem to establish the existence and uniqueness solutions of the model. In particular, the model identifies equilibrium points corresponding to disease outbreaks and disease-free scenarios.

    Additionally, it showcases the local asymptotic stability of the disease-free equilibrium point and outlines the criteria for the presence of the endemic equilibrium point.

    The findings verify that as the fractional order decreases, the disease-free equilibrium point becomes more stable. To demonstrate the impact of altering the fractional order and to bolster the theoretical finding, numerical simulations are conducted over the fractional order range.


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