Scaffolded Structure Determination Activities Utilizing 2D NMR Spectroscopy of Simple Organic Molecules

• Amelia M. Anderson-Wile ^[1] ; Kelly E. Hall ^[1] ; Tevye C. Celius ^[1]
  1. [1] Ohio Northern University, United States
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 101, Nº 3, 2024, págs. 1356-1360
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • A structured series of activities has been designed and implemented to promote analysis and data reporting skills for second-year organic chemistry students. Student report sheets were developed to assist students in reporting necessary data for their compounds. A series of rubrics have been utilized by students to promote metacognition and by faculty to promote equitable evaluation. Complete spectral data has been provided for twenty-one student samples; however, the report sheets and rubrics could be used with any unknown organic molecule. In addition to traditional 1D NMR spectra (1H, 13C, DEPT-135), 2D NMR spectroscopy data (1H–1H COSY and 1H–13C HSQC) has been incorporated into a structure determination laboratory experiment for second-year organic chemistry students. The experiment described here has been delivered both as both an in-person classroom activity and a remote laboratory experience.