Treatments for non-small cell lung cancer: a systematic quality assessment of clinical practice guidelines

• Marcela Cortés-Jofré ^[1] ; Meisser Madera ^[2] ; Lesbia Tirado-Amador ^[3] ; Claudia Asenjo-Lobos ^[4] ; Xavier Bonfill-Cosp ^[5]
  1. [1] Universidad Católica de la Santísima Concepción

     Universidad Católica de la Santísima Concepción

     Comuna de Concepción, Chile

     
  2. [2] Universidad de Cartagena

     Universidad de Cartagena

     Colombia

     
  3. [3] Universidad del Sinú

     Universidad del Sinú

     Colombia

     
  4. [4] Centro de Estudios Clínicos, Instituto de Ciencias e Innovación en Medicina (ICIM), Facultad de Medicina Clínica Alemana, Universidad de Desarrollo, Santiago, Chile
  5. [5] Centro Cochrane Iberoamericano, Instituto de Investigación Biomédica Sant Pau (IIB Sant Pau), Barcelona, España

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• Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 25, Nº. 12 (December), 2023, págs. 3541-3555
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Aim To evaluate the methodological quality of clinical practice guidelines (CPGs) on treatments for non-small cell lung cancer (NSCLC).

    Methods We searched MEDLINE, CPG developer websites, lung cancer societies, and oncology organizations to identify CPGs providing recommendations on treatments for NSCLC. The methodological quality for each CPG was determined independently by three appraisers using the AGREE II (Appraisal of Guidelines for Research and Evaluation II) instrument.

    Results Twenty-two CPGs met the eligibility criteria. The median scores per AGREE II domain were: scope and purpose 90.7% (64.8–100%), stakeholder involvement 76.9% (27.8–96.3%); rigor of development 80.9% (27.1–92.4%); clarity of presentation 89.8% (50–100%); applicability 46.5% (12.5–87.5%); and editorial independence 91.7% (27.8–100%). Most of the CPGs (54.5%) were rated as “recommended with modifications” for clinical use.

    Conclusions Overall, the methodological quality of CPGs proving recommendations on the management of NSCLC is moderate, but there is still room for improvement in their development and implementation.