Circular RNAs-mediated angiogenesis in human cancers

• Farhoodeh Ghaedrahmati ^[1] ; Ava Nasrolahi ^[6] ; Sajad Najafi ^[2] ; Mohammad Mighani ^[3] ; Omid Anbiyaee ^[4] ; Habib Haybar ^[7] ; Ahmad Reza Assareh ^[7] ; Bartosz Kempisty ^[8] ; Piotr Dzięgiel ^[5] ; Shirin Azizidoost ^[7] ; Maryam Farzaneh ^[9]
  1. [1] Isfahan University of Medical Sciences

     Isfahan University of Medical Sciences

     Irán

     
  2. [2] Shahid Beheshti University of Medical Sciences

     Shahid Beheshti University of Medical Sciences

     Irán

     
  3. [3] Golestan University of Medical Sciences

     Golestan University of Medical Sciences

     Irán

     
  4. [4] Shiraz University of Medical Sciences

     Shiraz University of Medical Sciences

     Irán

     
  5. [5] Wrocław Medical University

     Wrocław Medical University

     Breslavia, Polonia

     
  6. [6] Infectious Ophthalmologic Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  7. [7] Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  8. [8] Institute of Veterinary Medicine, Department of Veterinary Surgery, Nicolaus Copernicus University, Torun, Poland
  9. [9] Fertility, Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

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• Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 25, Nº. 11 (November), 2023, págs. 3101-3121
• Idioma: inglés
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• Resumen

  • Circular RNAs (circRNAs) as small non-coding RNAs with cell, tissue, or organ-specific expression accomplish a broad array of functions in physiological and pathological processes such as cancer development. Angiogenesis, a complicated multistep process driving a formation of new blood vessels, speeds up tumor progression by supplying nutrients as well as energy. Abnormal expression of circRNAs reported to affect tumor development through impressing angiogenesis. Such impacts are introduced as constant with different tumorigenic features known as “hallmarks of cancer”. In addition, deregulated circRNAs show possibilities to prognosis and diagnosis both in the prophecy of prognosis in malignancies and also their prejudice from healthy individuals. In the present review article, we have evaluated the angiogenic impacts and anti-angiogenic managements of circRNAs in human cancers.