Transcranial direct current stimulation (tDCS) is a noninvasive technique for brain stimulation capable of modulating brainexcitability. Although beneficial effects of tDCS have been shown, the underlying brain mechanisms have not been described. In the present study, we aim to investigate the effects of tDCS on EEG-based functional connectivity, through a partial directed coherence (PDC) analysis, which is a frequency-domain metric that provides information about directionality in the interaction between signals recorded at different channels.The tDCS montage used in our study, was focused on the lower limbs and it was composed of two anodes and one cathode. A single-blind study was carried out, where eight healthy subjects were randomly separated into two groups: sham and active tDCS. Results showed that, for the active tDCS group, the central EEG electrodes Cz, C3 and C4 turned out to be highly connected within alpha and beta frequency bands.On the contrary, the sham group presented a tendency to be more random at its functional connections.
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