Gingival neoplasms: a multicenter collaborative study of 888 patients in Brazil

• Éder Gerardo Santos-Leite ^[6] ; Brendo Vinicius Rodrigues Louredo ^[6] ; Lucas Lacerda de Souza ^[6] ; Helder Antônio Rebelo Pontes ^[7] ; Flávia Sirotheau Correa Pontes ^[1] ; Jean Nunes dos Santos ^[2] ; Águida Cristina Gomes Henriques ^[2] ; Jurema Freire Lisboa de Castro ^[3] ; Elaine Judite de Amorim Carvalho ^[3] ; Augusto César Leal da Silva Leonel ^[3] ; Raylane Farias de Albuquerque ^[3] ; Thayanne Oliveira de Freitas Gonçalves ^[4] ; Aline Corrêa Abrahão ^[4] ; Michelle Agostini ^[4] ; Mario José Romañach ^[4] ; Vinicius Coelho Carrard ^[5] ; Manoela Domingues Martins ^[5] ; Teresa Cristina Ribeiro Bartholomeu dos Santos ^[8] ; Fábio Ramôa Pires ^[8] ; Alan Roger Santos-Silva ^[6] ; Márcio Ajudarte Lopes ^[6] ; Pablo Agustin Vargas ^[6] ; Danyel Elias da Cruz Perez ^[3]
  1. [1] Universidad Federal de Pará

     Universidad Federal de Pará

     Brasil

     
  2. [2] Universidade Federal da Bahia

     Universidade Federal da Bahia

     Brasil

     
  3. [3] Universidade Federal de Pernambuco

     Universidade Federal de Pernambuco

     Brasil

     
  4. [4] Universidade Federal do Rio de Janeiro

     Universidade Federal do Rio de Janeiro

     Brasil

     
  5. [5] Universidade Federal do Rio Grande do Sul

     Universidade Federal do Rio Grande do Sul

     Brasil

     
  6. [6] Oral Diagnosis Department, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil
  7. [7] Oral Diagnosis Department, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil; Oral Pathology Unit, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Pará, Brazil
  8. [8] Oral Pathology Department, School of Dentistry, State University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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• Localización: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, ISSN-e 1698-6946, Vol. 28, Nº. 4 (July), 2023
• Idioma: inglés
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• Resumen

  • To evaluate the prevalence and clinicopathological features of a large series of gingival neoplasms in Brazil.

     All gingival benign and malignant neoplasms were retrieved from the records of six Oral Pathology Services in Brazil, during a 41-year period. Clinical and demographic data, clinical diagnosis, and histopathological data were collected from the patients' clinical charts. For statistical analysis, the chi-square, median test of independent samples and the U Mann-Whitney tests were used, considering a significance of 5%.

     From 100,026 oral lesions, 888 (0.9%) were gingival neoplasms. There were 496 (55.9%) males, with a mean age of 54.2 years. Most cases (70.3%) were malignant neoplasms. Nodules (46.2%) and ulcers (38.9%) were the most common clinical appearance for benign and malignant neoplasms, respectively. Squamous cell carcinoma (55.6%) was the most common gingival neoplasm, followed by squamous cell papilloma (19.6%). In 69 (11.1%) malignant neoplasms, the lesions were clinically considered to be inflammatory or of infectious origin. Malignant neoplasms were more common in older men, appeared with larger size, and with a time of complaint shorter than benign neoplasms (p<0.001).

     Benign and malignant tumors may appear as nodules in gingival tissue. In addition, malignant neoplasms, especially squamous cell carcinoma, should be considered in the differential diagnosis of persistent single gingival ulcers.