F. Arroyo Balán, M. Eugenia López Arellano, E. Liébano Hernández, Víctor Manuel Vázquez Prats, A. Ortiz de Montellano, Maria Sol Arias Vázquez, Cristiana Filipa Cazapal Monteiro, P. Mendoza-De Gives
The aim of this research was to evaluate the efficacy of a combined method of parasitic control, with albendazole and Duddingtonia flagrans chlamydospores in Haemonchus contortus artificially infected sheep. Forty H. contortus-infected sheep were used. This experiment was carried out in a 90-day period. Sheep were ramdomly divided into four groups of 10 animals each and received the following treatments: Group 1, albendazole at 7.5 mg/kg at days 0, 30 and 60; Group 2, received an oral treatment with 1x106 D. flagrans chlamydospores per kilogram; Group 3 received a combined treatment: albendazole was orally administered twice, at days 1 and 60 at the previously mentioned dose, and was also orally treated with D. flagrans chlamydospores everyday from day 30 to day 60 at the same dose than group 2; Group 4 (control group). Results showed a high anthelmintic efficacy (91%) for albendazole; meanwhile, the biological and the combined methods resulted in 69 and 79% larval reduction in fecal cultures; respectively and the three groups showed statistic differences with respect to the control group. The combined method using albendazole and D. flagrans chlamydospores is a promissory alternative against the ovine haemonchosis.
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